Sleep Eazy is a natural sleep aid that contains specific ingredients that may help in improving sleep quality, sleep onset (time to fall as sleep) and total sleep duration.

As you may know, your sleep is one of the biggest factors in overall health, daily energy, weight loss, binge eating and hunger, sports performance, cognitive function and muscle growth. By optimizing sleep, you can maximize your efforts in the gym, recover faster and train harder. No matter your goals, a good, deep night’s sleep is essential.

Research & References

1.) Van Geijlswijk, I. M., Mol, R. H., Egberts, T. C., & Smits, M. G. (2011). Evaluation of sleep, puberty and mental health in children with long-term melatonin treatment for chronic idiopathic childhood sleep onset insomnia. Psychopharmacology, 216(1), 111-120.

2.) Lemoine, P., Nir, T., Laudon, M., & Zisapel, N. (2007). Prolonged‐release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. Journal of sleep research, 16(4), 372-380.

3.) Luthringer, R., Muzet, M., Zisapel, N., & Staner, L. (2009). The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. International clinical psychopharmacology, 24(5), 239-249.

4.) Alstadhaug, K. B., Odeh, F., Salvesen, R., & Bekkelund, S. I. (2010). Prophylaxis of migraine with melatonin A randomized controlled trial. Neurology, 75(17), 1527-1532.

5.) Celinski, K., Konturek, P. C., Konturek, S. J., Slomka, M., Cichoz-Lach, H., Brzozowski, T., & Bielanski, W. (2011). Effects of melatonin and tryptophan on healing of gastric and duodenal ulcers with Helicobacter pylori infection in humans. Journal of Physiology and Pharmacology, 62(5), 521.

6.) Konturek, P. C., Konturek, S. J., Celinski, K., Slomka, M., Cichoz‐Lach, H., Bielanski, W., & Reiter, R. J. (2010). Role of melatonin in mucosal gastroprotection against aspirin‐induced gastric lesions in humans. Journal of pineal research, 48(4), 318-323.

7.) Celinski, K., Konturek, S. J., Konturek, P. C., Brzozowski, T., Cichoz‐Lach, H., Slomka, M., … & Reiter, R. J. (2011). Melatonin or l‐tryptophan accelerates healing of gastroduodenal ulcers in patients treated with omeprazole. Journal of pineal research, 50(4), 389-394.

8.) Gonciarz, M., Bielański, W., Partyka, R., Brzozowski, T., Konturek, P. C., Eszyk, J., … & Konturek, S. J. (2013). Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin. Journal of pineal research, 54(2), 154-161.

9.) Kandil, T. S., Mousa, A. A., El-Gendy, A. A., & Abbas, A. M. (2010). The potential therapeutic effect of melatonin in gastro-esophageal reflux disease. BMC gastroenterology, 10(1), 7.

10.) Cagnacci, A., Arangino, S., Angiolucci, M., Maschio, E., & Melis, G. B. (1998). Influences of melatonin administration on the circulation of women. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 274(2), R335-R338.

11.) Herxheimer, A., & Petrie, K. J. (2002). Melatonin for the prevention and treatment of jet lag. The Cochrane Library.

12.) Koziróg, M., Poliwczak, A. R., Duchnowicz, P., Koter‐Michalak, M., Sikora, J., & Broncel, M. (2011). Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. Journal of pineal research, 50(3), 261-266.

13.) Nishiyama, K., Yasue, H., Moriyama, Y., Tsunoda, R., Ogawa, H., Yoshimura, M., & Kugiyama, K. (2001). Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men. American heart journal, 141(5), 13A-17A.

14.) Megwalu, U. C., Finnell, J. E., & Piccirillo, J. F. (2006). The effects of melatonin on tinnitus and sleep. Otolaryngology—Head and Neck Surgery, 134(2), 210-213.

15.) Hurtuk, A., Dome, C., Holloman, C. H., Wolfe, K., Welling, D. B., Dodson, E. E., & Jacob, A. (2011). Melatonin: can it stop the ringing?. Annals of Otology, Rhinology & Laryngology, 120(7), 433-440.

16.) Lemoine, P., Nir, T., Laudon, M., & Zisapel, N. (2007). Prolonged‐release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. Journal of sleep research, 16(4), 372-380.

17.) Luthringer, R., Muzet, M., Zisapel, N., & Staner, L. (2009). The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. International clinical psychopharmacology, 24(5), 239-249.

18.) Rimmele, U., Spillmann, M., Bärtschi, C., Wolf, O. T., Weber, C. S., Ehlert, U., & Wirtz, P. H. (2009). Melatonin improves memory acquisition under stress independent of stress hormone release. Psychopharmacology, 202(4), 663-672.

19.) Forsling, M. L., Wheeler, M. J., & Williams, A. J. (1999). The effect of melatonin administration on pituitary hormone secretion in man. Clinical endocrinology, 51(5), 637-642.

20.) Lu, K., Gray, M. A., Oliver, C., Liley, D. T., Harrison, B. J., Bartholomeusz, C. F., … & Nathan, P. J. (2004). The acute effects of L‐theanine in comparison with alprazolam on anticipatory anxiety in humans. Human Psychopharmacology: Clinical and Experimental, 19(7), 457-465.

21.) Higashiyama, A., Htay, H. H., Ozeki, M., Juneja, L. R., & Kapoor, M. P. (2011). Effects of L-theanine on attention and reaction time response. Journal of Functional Foods, 3(3), 171-178.

22.) Song, C. H., Jung, J. H., Oh, J. S., & Kim, K. S. (2003). Effects of theanine on the release of brain alpha wave in adult males. Korean Journal of Nutrition, 36(9), 918-923.

23.) Ritsner, M. S., Miodownik, C., Ratner, Y., Shleifer, T., Mar, M., Pintov, L., & Lerner, V. (2011). L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. Journal of Clinical Psychiatry, 72(1), 34.

24.) Kimura, K., Ozeki, M., Juneja, L. R., & Ohira, H. (2007). L-Theanine reduces psychological and physiological stress responses. Biological psychology, 74(1), 39-45.

25.) Lyon, M. R., Kapoor, M. P., & Juneja, L. R. (2011). The effects of L-theanine (Suntheanine) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev, 16(4), 348-354.

26.) Cangiano, C., Ceci, F., Cascino, A., Del Ben, M., Laviano, A., Muscaritoli, M., … & Rossi-Fanelli, F. (1992). Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. The American journal of clinical nutrition, 56(5), 863-867.

27.) Cangiano, C., Laviano, A., Del Ben, M., Preziosa, I., Angelico, F., Cascino, A., & Rossi-Fanelli, F. (1998). Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients. International journal of Obesity, 22(7), 648-654.

28.) Ceci, F., Cangiano, C., Cairella, M., Cascino, A., Del Ben, M., Muscaritoli, M., … & Rossi Fanelli, F. (1989). The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. Journal of neural transmission, 76(2), 109-117.

29.) Guilleminault, C., Palombini, L., Pelayo, R., & Chervin, R. D. (2003). Sleepwalking and sleep terrors in prepubertal children: what triggers them?. Pediatrics, 111(1), e17-e25.

30.) Guerrero‐Romero, F., & Rodríguez‐Morán, M. (2011). Magnesium improves the beta‐cell function to compensate variation of insulin sensitivity: double‐blind, randomized clinical trial. European journal of clinical investigation, 41(4), 405-410.

31.) Hatzistavri, L. S., Sarafidis, P. A., Georgianos, P. I., Tziolas, I. M., Aroditis, C. P., Zebekakis, P. E., … & Lasaridis, A. N. (2009). Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. American journal of hypertension, 22(10), 1070-1075.

32.) Guerrero-Romero, F., & Rodriguez-Moran, M. (2009). The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial. Journal of human hypertension, 23(4), 245-251.

33.) Kawano, Y., Matsuoka, H., Takishita, S., & Omae, T. (1998). Effects of magnesium supplementation in hypertensive patients. Hypertension, 32(2), 260-265.

34.) Mooren, F. C., Krüger, K., Völker, K., Golf, S. W., Wadepuhl, M., & Kraus, A. (2011). Oral magnesium supplementation reduces insulin resistance in non‐diabetic subjects–a double‐blind, placebo‐controlled, randomized trial. Diabetes, Obesity and Metabolism, 13(3), 281-284.

35.) Rodríguez-Morán, M., & Guerrero-Romero, F. (2003). Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects. Diabetes care, 26(4), 1147-1152.

36.) Golf, S. W., Bender, S., & Grüttner, J. (1998). On the significance of magnesium in extreme physical stress. Cardiovascular Drugs and Therapy, 12, 197-202.

37.) Held, K., Antonijevic, I. A., Künzel, H., Uhr, M., Wetter, T. C., Golly, I. C., … & Murck, H. (2002). Oral Mg2+ supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry, 35(04), 135-143.

38.) Nielsen, F. H., Johnson, L. K., & Zeng, H. (2010). Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnesium Research, 23(4), 158-168.

39.) Quaranta, S., Buscaglia, M. A., Meroni, M. G., Colombo, E., & Cella, S. (2007). Pilot study of the efficacy and safety of a modified-release magnesium 250mg tablet (Sincromag®) for the treatment of premenstrual syndrome. Clinical drug investigation, 27(1), 51-58.

40.) Barragán-Rodríguez, L., Rodríguez-Morán, M., & Guerrero-Romero, F. (2008). Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial. Magnesium Research, 21(4), 218-223.

41.) Petroff, O. A. (2002). Book review: GABA and glutamate in the human brain. The Neuroscientist, 8(6), 562-573.

42.) Elio, F., Gatti, R., Antonelli, G., & Spinella, P. (2006). Growth hormone isoforms, segments/fragments: Does a link exist with multifunctionality?. Clinica chimica acta, 364(1), 77-81.

43.) Powers, M. E., Yarrow, J. F., Mccoy, S. C., & Borst, S. E. (2008). Growth hormone isoform responses to GABA ingestion at rest and after exercise. Medicine and science in sports and exercise, 40(1), 104.

44.) Cavagnini, F., Invitti, C., Pinto, M., Maraschini, C., Di Landro, A., Dubini, A., & Marelli, A. (1980). Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta endocrinologica, 93(2), 149-154.

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